Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 11/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 11/20 | 0.43 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893525 | 1.00 | LPL (0.43) | LPLLIPGJAK2BTKALDH1A1 | |
| SCHEMBL16807317 | 1.00 | LPL (0.43) | LPLLIPGJAK2BTKALDH1A1 | |
| SCHEMBL22211893 | 0.89 | LPL (0.41) | LPLLIPGJAK2BTKALDH1A1 | |
| SCHEMBL18421333 | 0.87 | LIPG (0.45) | LPLLIPGP4HBEGFR | |
| SCHEMBL25622461 | 0.85 | CYP1A2 (0.45) | LPLLIPGJAK2BTKALDH1A1 | |
| SCHEMBL18090435 | 0.84 | MEN1 (0.37) | LPLLIPGJAK2BTKALDH1A1 | |
| SCHEMBL21331592 | 0.84 | CDC14B (0.33) | LPLLIPGJAK2BTKALDH1A1 | |
| SCHEMBL31759037 | 0.84 | CDC14B (0.33) | LPLLIPGJAK2BTKALDH1A1 | |
| SCHEMBL13527502 | 0.84 | LPL (0.44) | LPLLIPGJAK2BTKANPEP | |
| SCHEMBL24539770 | 0.83 | CDC14B (0.35) | LPLLIPGJAK2BTKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227269-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |