Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21764796 | 0.98 | LPAR3 (0.53) | LPAR3LPAR2LPAR1CYP3A4ALDH1A1 | |
| SCHEMBL21764713 | 0.94 | CYP3A4 (0.48) | LPAR3LPAR2LPAR1CYP3A4ALDH1A1 | |
| SCHEMBL21764583 | 0.86 | ALDH1A1 (0.35) | LPAR3LPAR2LPAR1CYP3A4ALDH1A1 | |
| SCHEMBL1194563 | 0.82 | LPAR3 (0.58) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL393907 | 0.80 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL17686773 | 0.80 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL21764574 | 0.80 | CYP3A4 (0.58) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL9463219 | 0.80 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL29085821 | 0.80 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL28954648 | 0.80 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3474860-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF USE | AEQUOR INC (US) | 2021-12-15 | — | — | EP | disclosed |
| US-20200060280-A1 | Antimicrobial Compounds and Methods of Use | AEQUOR, INC. | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200060280-A1 | Antimicrobial Compounds and Methods of Use | DDT, PFAS, DSTN | LPAR3 3397/4885LPAR2 3576/4885LPAR1 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.