Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNK18 | Q7Z418 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25786524 | 0.94 | KCNK18 (0.45) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20552969 | 0.88 | ABCG2 (0.43) | ALDH1A1MAPTSMN1; SMN2TAS2R14TP53 | |
| SCHEMBL21749307 | 0.87 | MAPT (0.49) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20552652 | 0.87 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20552415 | 0.87 | YAP1 (0.47) | YAP1TEAD4TEAD2RXFP1 | |
| SCHEMBL20553068 | 0.87 | CYP11B1 (0.44) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21749242 | 0.87 | TP53 (0.44) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20552892 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL25786417 | 0.83 | KCNK18 (0.47) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20552275 | 0.82 | YAP1 (0.47) | ALDH1A1MAPTSMN1; SMN2YAP1TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186554-B2 | Non-fused tricyclic compounds | VIVACE THERAPEUTICS, INC. (US) | 2021-11-30 | — | — | US | disclosed |
| US-20200062721-A1 | NON-FUSED TRICYCLIC COMPOUNDS | VIVACE THERAPEUTICS, INC. | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062721-A1 | NON-FUSED TRICYCLIC COMPOUNDS | YAP1, MYC, TEAD2 | ALDH1A1 3497/4885GAA 3437/4885MAPT 1705/4885 |
| US-11186554-B2 | Non-fused tricyclic compounds | YAP1, MYC, TEAD2 | ALDH1A1 3497/4885GAA 3437/4885MAPT 1705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.