SCHEMBL21765277

SCHEMBL21765277

CC(C)c1c(N)cc(I)cc1F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRB2 P47870 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21756924 0.84 GABRA1 (0.41) GABRA1GABRB1GABRB2
SCHEMBL21756930 0.77 GABRA1 (0.35) GABRA1GABRB1GABRB2
SCHEMBL21765276 0.77 GABRA1 (0.35) GABRA1GABRB1GABRB2
SCHEMBL21769673 0.75 GABRA1 (0.34) GABRA1GABRB1GABRB2
SCHEMBL21756949 0.75 GABRA1 (0.43) GABRA1GABRB1GABRB2
SCHEMBL21756927 0.75 GABRA1 (0.31) GABRA1GABRB1GABRB2
SCHEMBL21765275 0.73 GABRA1 (0.33) GABRA1GABRB1GABRB2
SCHEMBL24603727 0.72
SCHEMBL21765279 0.72 GABRA1 (0.32) GABRA1GABRB1GABRB2
SCHEMBL1548522 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020039088-A2 NOVEL COMPOUNDS Xeniopro GmbH (DE) 2020-02-27 WO disclosed
WO-2020039094-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY Xeniopro GmbH (DE) 2020-02-27 WO disclosed