Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753304 | 0.88 | TACR1 (0.46) | MGLLPPARDGPR119NAMPTTACR1 | |
| SCHEMBL209368 | 0.80 | PPARD (0.59) | MGLLPPARDGPR119MEN1KMT2A | |
| SCHEMBL26081084 | 0.80 | MGLL (0.46) | MGLLPPARDGPR119TACR1OPRD1 | |
| SCHEMBL3661148 | 0.79 | GPR119 (0.44) | MGLLGPR119NAMPTTACR1 | |
| SCHEMBL30328599 | 0.78 | TACR1 (0.47) | PPARDGPR119TACR1MEN1KMT2A | |
| SCHEMBL14155585 | 0.78 | NAMPT (0.46) | MGLLNAMPT | |
| SCHEMBL25291826 | 0.77 | PPARD (0.51) | MGLLPPARDGPR119NAMPTMEN1 | |
| SCHEMBL21608013 | 0.77 | PPARD (0.54) | MGLLPPARDGPR119MEN1KMT2A | |
| SCHEMBL22719293 | 0.77 | MGLL (0.43) | MGLLPPARDGPR119TACR1JAK2 | |
| SCHEMBL3490742 | 0.76 | NAMPT (0.45) | MGLLNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039029-A1 | SPIRO COMPOUNDS AS GLYCOSIDASE INHIBITORS | ASCENEURON S. A. (CH) | 2020-02-27 | — | — | WO | disclosed |