Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.53 |
| ▸ | TNF | P01375 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765615 | 0.86 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL31436622 | 0.86 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL26598605 | 0.86 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL18341474 | 0.82 | IRAK4 (0.65) | IRAK4 | |
| SCHEMBL21379161 | 0.82 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL18882610 | 0.82 | IRAK4 (0.64) | IRAK4TNF | |
| SCHEMBL21379077 | 0.81 | IRAK4 (0.57) | IRAK4TNF | |
| SCHEMBL18341624 | 0.81 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL16873174 | 0.81 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL21379047 | 0.81 | IRAK4 (0.57) | IRAK4TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475270-B1 | HETEROARYL SUBSTITUTED AMINOPYRIDINE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-02-26 | — | — | EP | disclosed |