SCHEMBL2176562

SCHEMBL2176562

CCC(C)OC(Cc1ccc(-c2cccc(NC)c2)cc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SRR Q9GZT4 2/20 0.46
PSAT1 Q9Y617 2/20 0.46
PPARG P37231 11/20 0.46
PPARA Q07869 9/20 0.46
ITGB3 P05106 7/20 0.44
ITGAV P06756 7/20 0.44
PPARD Q03181 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2177187 0.85 SRR (0.48) SRRPSAT1PPARGPPARAITGB3
SCHEMBL3147855 0.83 ITGB3 (0.47) SRRPSAT1PPARGPPARAITGB3
SCHEMBL3147868 0.83 ITGB3 (0.47) SRRPSAT1PPARGPPARAITGB3
SCHEMBL3187411 0.81 PPARG (0.52) SRRPSAT1PPARGPPARAITGB3
SCHEMBL3187393 0.81 PPARG (0.52) SRRPSAT1PPARGPPARAITGB3
SCHEMBL3146484 0.78 SRR (0.44) SRRPSAT1PPARGPPARAITGB3
SCHEMBL3146470 0.78 SRR (0.44) SRRPSAT1PPARGPPARAITGB3
SCHEMBL2174166 0.77 SRR (0.43) SRRPSAT1PPARGPPARAITGB3
SCHEMBL2853722 0.77 GRIA2 (0.53) ITGB3ITGAV
SCHEMBL2853719 0.77 GRIA2 (0.53) ITGB3ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7973063-B2 Methods for activating PPAR gamma-type receptors GALDERMA RESEARCH & DEVELOPMENT (FR) 2011-07-05 US disclosed