Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL600235 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TSHRHPGDTAS1R3TAS1R1 | |
| SCHEMBL6390944 | 0.85 | ALDH1A1 (0.61) | ALDH1A1TSHRHPGDTAS1R3TAS1R1 | |
| SCHEMBL4010530 | 0.82 | ALDH1A1 (0.74) | ALDH1A1TSHRHPGDHTTPOLB | |
| SCHEMBL4003611 | 0.82 | ALDH1A1 (0.74) | ALDH1A1TSHRHPGDHTTPOLB | |
| SCHEMBL4009579 | 0.82 | ALDH1A1 (0.74) | ALDH1A1TSHRHPGDHTTPOLB | |
| SCHEMBL21765891 | 0.81 | MTNR1A (0.51) | ALDH1A1TSHRHPGDTAS1R3TAS1R1 | |
| SCHEMBL7469538 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRHPGD | |
| SCHEMBL23518507 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRHPGDTAS1R3TAS1R1 | |
| SCHEMBL21765892 | 0.76 | MTNR1A (0.47) | ALDH1A1TSHR | |
| SCHEMBL12828264 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRHPGDTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |