Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21283229 | 0.82 | — | — | |
| SCHEMBL18363122 | 0.80 | — | — | |
| SCHEMBL7543479 | 0.80 | CHRNB2 (0.38) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL15335091 | 0.80 | — | — | |
| SCHEMBL16963370 | 0.80 | NR1H2 (0.58) | KDM4EMEN1USP2ALDH1A1HPGD | |
| SCHEMBL16963368 | 0.80 | NR1H2 (0.58) | KDM4EMEN1USP2ALDH1A1HPGD | |
| SCHEMBL1150850 | 0.77 | ALDH1A1 (0.46) | CHRNB2CHRNA3CHRNA4KDM4EMEN1 | |
| SCHEMBL16963150 | 0.75 | ALDH1A1 (0.36) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL13886444 | 0.75 | CHRNB2 (0.34) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7 | |
| SCHEMBL11581015 | 0.75 | KDM4E (0.42) | KDM4EMEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |