Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | BRD4 | O60885 | 3/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765696 | 0.93 | POLB (0.57) | POLBBRD4NOTUMCYP2C9CYP1A2 | |
| SCHEMBL27793255 | 0.81 | POLB (0.48) | POLBBRD4NOTUMCYP2C9CYP1A2 | |
| SCHEMBL9607910 | 0.78 | NOTUM (0.58) | POLBBRD4NOTUMCYP2C9CYP2D6 | |
| SCHEMBL20571442 | 0.78 | HDAC1 (0.55) | POLBNOTUMCYP2C9CYP1A2CYP2C19 | |
| SCHEMBL5006023 | 0.77 | TSHR (0.75) | POLBNOTUMTSHRMEN1KMT2A | |
| SCHEMBL22605860 | 0.76 | NOTUM (0.56) | POLBBRD4NOTUMCYP2C9CYP2D6 | |
| SCHEMBL31053915 | 0.76 | POLB (0.43) | POLBCYP2C9CYP1A2CYP2C19TSHR | |
| SCHEMBL21765659 | 0.75 | TSHR (0.52) | POLBBRD4NOTUMTSHRMEN1 | |
| SCHEMBL23174879 | 0.75 | POLB (0.44) | POLBNOTUMCYP2C9CYP1A2CYP2C19 | |
| SCHEMBL29520673 | 0.75 | NOTUM (0.69) | POLBNOTUMTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |