Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660180 | 1.00 | NOTUM (0.69) | NOTUMSMN1; SMN2ALDH1A1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL29520826 | 0.98 | NOTUM (0.67) | NOTUMSMN1; SMN2ALDH1A1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL29521106 | 0.98 | NOTUM (0.67) | NOTUMSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL24925819 | 0.95 | ALDH1A1 (0.62) | NOTUMSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL5006023 | 0.90 | TSHR (0.75) | NOTUMSMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL711283 | 0.88 | TSHR (0.67) | NOTUMSMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL29522633 | 0.88 | TSHR (0.67) | NOTUMSMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL1545217 | 0.85 | SMN1; SMN2 (0.70) | NOTUMSMN1; SMN2ALDH1A1TSHRMAPK1 | |
| SCHEMBL9278163 | 0.84 | SMN1; SMN2 (0.73) | NOTUMSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL3089154 | 0.84 | SMN1; SMN2 (0.68) | NOTUMSMN1; SMN2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936468-B | Compounds with anticancer activity | 协和麒麟株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-114502534-A | BET degradant | 协和麒麟株式会社 | 2022-05-13 | — | — | CN | disclosed |