Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765698 | 0.93 | POLB (0.68) | POLBCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL20571442 | 0.84 | HDAC1 (0.55) | POLBCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL5006023 | 0.83 | TSHR (0.75) | POLBTSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31053915 | 0.82 | POLB (0.43) | POLBCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL21765659 | 0.81 | TSHR (0.52) | POLBTSHRALDH1A1KDM4EBRD4 | |
| SCHEMBL23174879 | 0.81 | POLB (0.44) | POLBCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL29520673 | 0.81 | NOTUM (0.69) | POLBTSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3660180 | 0.81 | NOTUM (0.69) | POLBTSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13525163 | 0.79 | NOTUM (0.69) | POLBCYP2C19ALDH1A1MAPTKMT2A | |
| SCHEMBL24925819 | 0.79 | ALDH1A1 (0.62) | POLBTSHRALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |