SCHEMBL21765780

SCHEMBL21765780

N#Cc1c(-n2c3ccccc3c3ccccc32)c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c(-c2ccccc2)c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c1-n1c2ccccc2c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE9A O76083 2/20 0.39
PDE1C Q14123 1/20 0.39
HTR3A P46098 1/20 0.39
TSPO P30536 1/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 4/20 0.37
RXFP1 Q9HBX9 2/20 0.37
LMNA P02545 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37
GRIA4 P48058 2/20 0.36
GRIA2 P42262 1/20 0.36
MAPK1 P28482 1/20 0.35
STAT3 P40763 1/20 0.35
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAPT P10636 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PARP1 P09874 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20596032 1.00 PDE9A (0.39) PDE9APDE1CHTR3ATSPOALDH1A1
SCHEMBL22250955 1.00 PDE9A (0.39) PDE9APDE1CHTR3ATSPOALDH1A1
SCHEMBL20596020 1.00 PDE9A (0.39) PDE9APDE1CHTR3ATSPOALDH1A1
SCHEMBL20596627 1.00 PDE9A (0.39) PDE9APDE1CHTR3ATSPOALDH1A1
SCHEMBL22251505 1.00 PDE9A (0.39) PDE9APDE1CHTR3ATSPOALDH1A1
SCHEMBL20596603 1.00 PDE9A (0.39) PDE9APDE1CHTR3ATSPOALDH1A1
SCHEMBL23464423 0.97 PDE9A (0.38) PDE9APDE1CHTR3ATSPOALDH1A1
SCHEMBL20596401 0.97 PDE9A (0.38) PDE9APDE1CHTR3ATSPOALDH1A1
SCHEMBL21840874 0.97 PDE9A (0.38) PDE9APDE1CHTR3ATSPOALDH1A1
SCHEMBL24238062 0.97 PDE9A (0.39) PDE9APDE1CHTR3ATSPOALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023437-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND DESIGN METHOD AND PROGRAM FOR LIGHT EMITTING COMPOSITION KYULUX, INC. (JP) 2024-01-18 US disclosed
US-20240023437-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND DESIGN METHOD AND PROGRAM FOR LIGHT EMITTING COMPOSITION KYULUX, INC. (JP) 2024-01-18 US disclosed
US-20230225203-A1 ORGANIC LUMINESCENT ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20230225203-A1 ORGANIC LUMINESCENT ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20230209847-A1 ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2023-06-29 US disclosed
US-20230209847-A1 ORGANIC LIGHT EMITTING ELEMENT KYULUX, INC. (JP) 2023-06-29 US disclosed
US-20220223798-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-07-14 US disclosed
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT KYULUX, INC. (JP) 2021-07-01 US disclosed
US-20200235313-A1 COMPOUND, LIGHT-EMITTING MATERIAL AND LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2020-07-23 US disclosed
WO-2020039708-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT 国立大学法人九州大学 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200235313-A1 COMPOUND, LIGHT-EMITTING MATERIAL AND LIGHT-EMITTING ELEMENT LBR, CTNND1, NCL PDE9A 4324/4885PDE1C 4672/4885HTR3A 3601/4885
US-20210202864-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, EMC1, EEA1 PDE9A 3977/4885PDE1C 4656/4885HTR3A 4312/4885
US-20220223798-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE CHRM2, CCND3, CCNE2 PDE9A 4016/4885PDE1C 4605/4885HTR3A 1438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.