Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14033071 | 0.90 | RECQL (0.68) | POLBKMT2AMEN1L3MBTL1RECQL | |
| SCHEMBL7225647 | 0.86 | TSHR (0.57) | POLBKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL8788041 | 0.84 | ALDH1A1 (0.67) | RAB9AKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL12092129 | 0.84 | KMT2A (0.53) | POLBRAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL8605571 | 0.81 | NPC1 (0.53) | POLBRAB9AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL23518485 | 0.80 | POLB (0.51) | POLBRAB9ANR4A1KMT2AMEN1 | |
| SCHEMBL8259957 | 0.80 | POLB (0.71) | POLBRAB9AKMT2AMEN1MAPT | |
| SCHEMBL10970617 | 0.78 | RAB9A (0.85) | POLBRAB9ANR4A1KMT2AMEN1 | |
| SCHEMBL8606580 | 0.78 | ALDH1A1 (0.59) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL3021287 | 0.77 | CYP1A1 (0.55) | POLBKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261257-A1 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |