Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286771 | 0.93 | MAPT (0.72) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL15267699 | 0.84 | KMT2A (0.60) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL21765844 | 0.81 | POLB (0.56) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16053638 | 0.80 | ACP1 (0.44) | MAPTMEN1KMT2APOLBCYP1A2 | |
| SCHEMBL14157781 | 0.79 | CYP3A4 (0.65) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL8481692 | 0.79 | TSHR (0.59) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL29688982 | 0.79 | POLB (0.76) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8533501 | 0.79 | POLB (0.76) | MAPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4004069 | 0.79 | CYP3A4 (0.69) | MAPTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9730282 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AL3MBTL1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |