Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209430 | 0.91 | MAPT (0.44) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19193983 | 0.90 | MAPT (0.51) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7024703 | 0.90 | TAAR1 (0.50) | LMNATAAR1IDO1 | |
| SCHEMBL7447844 | 0.88 | MAOB (0.47) | NPC1RAB9AMEN1KMT2ABCHE | |
| SCHEMBL515186 | 0.80 | MAPT (0.56) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL10299392 | 0.80 | IDO1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21524730 | 0.79 | TAAR1 (0.41) | HRH3MAPTKDM4EMEN1KMT2A | |
| SCHEMBL19194006 | 0.79 | HDAC8 (0.44) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL11547033 | 0.78 | ESR1 (0.50) | MAPTNPC1RAB9ALMNAKDM4E | |
| SCHEMBL15962378 | 0.78 | LMNA (0.41) | MAPTNPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261257-A1 | STAPLED PEPTIDES AND METHODS THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |