Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDXK | O00764 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17917631 | 0.79 | ALDH1A1 (0.48) | NPC1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL21753564 | 0.76 | NPC1 (0.44) | NPC1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL20874552 | 0.76 | GAA (0.51) | NPC1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1326752 | 0.76 | KDM4E (0.51) | NPC1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL26924428 | 0.76 | NPC1 (0.44) | NPC1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL21753597 | 0.76 | KDM4E (0.45) | NPC1ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL23134841 | 0.75 | SMN1; SMN2 (0.40) | NPC1ATMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17914524 | 0.74 | NPC1 (0.42) | NPC1ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL5416311 | 0.71 | MAPT (0.57) | NPC1ALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL19436519 | 0.69 | NPC1 (0.44) | NPC1ALDH1A1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038387-A1 | HIGH ACTIVITY STING PROTEIN AGONIST | 杭州阿诺生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |