Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 11/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 5/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | NEK4 | P51957 | 1/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766191 | 0.92 | STING1 (0.40) | STING1ENPP1ITK | |
| SCHEMBL21766188 | 0.85 | STING1 (0.38) | STING1ENPP1ITKADORA2AIRAK4 | |
| SCHEMBL21766500 | 0.84 | ENPP1 (0.36) | STING1ENPP1ITKIRAK4MAP4K4 | |
| SCHEMBL23585761 | 0.78 | STING1 (0.48) | STING1TBK1 | |
| SCHEMBL23585751 | 0.75 | TTR (0.36) | ITKADORA2A | |
| SCHEMBL21766431 | 0.73 | ENPP1 (0.33) | STING1ENPP1SLC2A1SLC2A3SLC2A4 | |
| SCHEMBL21766530 | 0.72 | STING1 (0.34) | STING1ENPP1ITKIRAK4MAP4K4 | |
| SCHEMBL21766449 | 0.72 | ENPP1 (0.34) | STING1ENPP1ITKIRAK4MAP4K4 | |
| SCHEMBL21766434 | 0.71 | ENPP1 (0.33) | STING1ENPP1ITKSLC2A1SLC2A3 | |
| SCHEMBL21766351 | 0.71 | ENPP1 (0.53) | STING1ENPP1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038387-A1 | HIGH ACTIVITY STING PROTEIN AGONIST | 杭州阿诺生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |