Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766722 | 0.78 | — | — | |
| SCHEMBL21766798 | 0.75 | MEN1 (0.32) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19560661 | 0.73 | MEN1 (0.37) | MEN1KMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL19073904 | 0.71 | MEN1 (0.32) | MEN1KMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL17378389 | 0.69 | ALDH1A1 (0.38) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL19560711 | 0.69 | MEN1 (0.37) | MEN1KMT2AALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL389017 | 0.68 | — | — | |
| SCHEMBL20852338 | 0.67 | EPHX1 (0.32) | — | |
| SCHEMBL98447 | 0.66 | — | — | |
| SCHEMBL6358327 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402785-B1 | 3-(CARBOXYMETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |