Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18950872 | 0.83 | CRBN (0.31) | — | |
| SCHEMBL21766710 | 0.75 | MEN1 (0.32) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18629944 | 0.75 | — | — | |
| SCHEMBL18483031 | 0.73 | TAS2R38 (0.32) | — | |
| SCHEMBL16229843 | 0.73 | — | — | |
| SCHEMBL13972727 | 0.72 | — | — | |
| SCHEMBL7709783 | 0.72 | SMN1; SMN2 (0.35) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18286973 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL20198633 | 0.71 | HDAC3 (0.43) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19560661 | 0.69 | MEN1 (0.37) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402785-B1 | 3-(CARBOXYMETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |