Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 18/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.37 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898103 | 0.85 | ALK (0.69) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL29962304 | 0.85 | ALK (0.69) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL1755908 | 0.84 | ALK (0.50) | ALK | |
| SCHEMBL898280 | 0.81 | ALK (0.68) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL29962592 | 0.81 | ALK (0.68) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL10272638 | 0.80 | ALK (0.75) | ALK | |
| SCHEMBL7810179 | 0.77 | ALK (0.47) | ALK | |
| SCHEMBL20004950 | 0.76 | NOS3 (0.38) | ALK | |
| SCHEMBL1703114 | 0.74 | ALK (0.66) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL7810274 | 0.73 | ALK (0.47) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613729-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-26 | — | — | EP | disclosed |