Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | NOS2 | P35228 | 4/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766971 | 0.76 | ALK (0.50) | ALK | |
| SCHEMBL29962304 | 0.70 | ALK (0.69) | ALK | |
| SCHEMBL898103 | 0.70 | ALK (0.69) | ALK | |
| SCHEMBL17154500 | 0.66 | HTR7 (0.51) | HTR7KDM4EALDH1A1SMN1; SMN2HTR1B | |
| SCHEMBL7791992 | 0.66 | HTR7 (0.54) | HTR7KDM4EALDH1A1SMN1; SMN2HTR1B | |
| SCHEMBL898280 | 0.65 | ALK (0.68) | ALK | |
| SCHEMBL29962592 | 0.65 | ALK (0.68) | ALK | |
| SCHEMBL3583265 | 0.64 | ADORA2A (0.49) | NOS3NOS1NOS2HTR7KDM4E | |
| Hydrochloric Acid SCHEMBL11606266 | 0.64 | KCNA3 (0.61) | HTR7KDM4EALDH1A1SMN1; SMN2HTR1B | |
| SCHEMBL21443318 | 0.62 | HTR7 (0.37) | NOS3NOS1NOS2HTR7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |