Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767932 | 1.00 | MEN1 (0.69) | MEN1KMT2ACYP1A2ALDH1A1KIF11 | |
| SCHEMBL27338628 | 0.83 | MEN1 (0.71) | MEN1KMT2ACYP1A2ALDH1A1KIF11 | |
| SCHEMBL2089243 | 0.82 | CYP1A2 (0.70) | MEN1KMT2ACYP1A2ALDH1A1KIF11 | |
| SCHEMBL305912 | 0.82 | CYP1A2 (0.70) | MEN1KMT2ACYP1A2ALDH1A1KIF11 | |
| SCHEMBL2089245 | 0.82 | CYP1A2 (0.70) | MEN1KMT2ACYP1A2ALDH1A1KIF11 | |
| SCHEMBL7742622 | 0.81 | MEN1 (0.69) | MEN1KMT2ACYP1A2ALDH1A1KIF11 | |
| SCHEMBL13073529 | 0.81 | MEN1 (1.00) | MEN1KMT2ACYP1A2ALDH1A1TDP1 | |
| Water SCHEMBL8329268 | 0.81 | CYP1A2 (0.68) | MEN1KMT2ACYP1A2ALDH1A1KIF11 | |
| Hydrochloric Acid SCHEMBL1630962 | 0.81 | CYP1A2 (0.68) | MEN1KMT2ACYP1A2ALDH1A1KIF11 | |
| SCHEMBL27843752 | 0.81 | CYP1A2 (0.68) | MEN1KMT2ACYP1A2ALDH1A1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210115048-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-04-22 | — | — | US | disclosed |
| EP-3617208-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115048-A1 | HETEROCYCLIC COMPOUND | CASR, AGTR2, AGTR1 | MEN1 1763/4885KMT2A 2678/4885CYP1A2 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.