SCHEMBL21767937

SCHEMBL21767937

CC(C)CC(OC(=O)/C=C\C(=O)OC(CC(C)C)[Si](C(C)C)(C(C)C)C(C)C)[Si](C(C)C)(C(C)C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.39
LAP3 P28838 2/20 0.31
TSHR P16473 1/20 0.31
CYP19A1 P11511 1/20 0.30
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21767938 0.93 HCAR2 (0.52) HCAR2LAP3TSHR
SCHEMBL21767950 0.79 HCAR2 (0.38) HCAR2TSHR
SCHEMBL20377934 0.77 ATM (0.40) HCAR2TSHR
SCHEMBL20377937 0.77 ATM (0.40) HCAR2TSHR
SCHEMBL3482499 0.74 HCAR2 (0.48) HCAR2LAP3TSHRCYP19A1KEAP1
SCHEMBL11741771 0.74 HCAR2 (0.48) HCAR2LAP3TSHRCYP19A1KEAP1
SCHEMBL9719175 0.74 HCAR2 (0.48) HCAR2LAP3TSHRCYP19A1KEAP1
SCHEMBL21767939 0.73 HCAR2 (0.46) HCAR2KEAP1NFE2L2
SCHEMBL11774651 0.73 HCAR2 (0.46) HCAR2LAP3TSHRKEAP1NFE2L2
SCHEMBL5838503 0.72 HCAR2 (0.47) HCAR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3617240-B1 VEHICLE RESIN FOR AN ANTIFOULING COATING NIPPON PAINT MARINE COATINGS CO LTD (JP) 2021-12-01 EP disclosed
US-11111406-B2 Copolymer and antifouling coating composition containing the same NIPPON PAINT MARINE COATINGS CO., LTD. (JP) 2021-09-07 US disclosed
US-20210024770-A1 COPOLYMER AND ANTIFOULING COATING COMPOSITION CONTAINING THE SAME NIPPON PAINT MARINE COATINGS CO., LTD. (JP) 2021-01-28 US disclosed
EP-3617240-A1 COPOLYMER AND ANTI-FOULING PAINT COMPOSITION CONTAINING SAME Nippon Paint Marine Coatings Co., Ltd. (JP) 2020-03-04 EP disclosed