Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21782043 | 1.00 | ALDH1A1 (0.37) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21768206 | 1.00 | ALDH1A1 (0.37) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22068089 | 0.82 | GAA (0.40) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23726895 | 0.79 | SMN1; SMN2 (0.38) | ALDH1A1GAASMN1; SMN2TP53MAPT | |
| SCHEMBL21781967 | 0.79 | ALDH1A1 (0.30) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL29939188 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1GAASMN1; SMN2TP53MAPT | |
| SCHEMBL26544376 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1GAASMN1; SMN2TP53MAPT | |
| SCHEMBL17802980 | 0.77 | SMN1; SMN2 (0.43) | ALDH1A1GAASMN1; SMN2TP53MAPT | |
| SCHEMBL21781802 | 0.74 | OPRD1 (0.30) | — | |
| SCHEMBL8140913 | 0.72 | SMN1; SMN2 (0.42) | ALDH1A1GAANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110312730-B | Cytotoxins and conjugates, uses thereof and methods of preparation | 四川科伦博泰生物医药股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |