Diphenamide

Diphenamide

SCHEMBL2176920

CN(C)C(=O)C(c1ccccc1)c1ccccc1.OCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
ATM Q13315 1/20 0.53
TDP1 Q9NUW8 2/20 0.51
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
ALDH1A1 P00352 1/20 0.49
OPRM1 P35372 1/20 0.47
OPRL1 P41146 1/20 0.47
TACR1 P25103 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
GAA P10253 1/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenamide SCHEMBL6910614 0.92 ALDH1A1 (0.55) KDM4EATMTDP1MEN1KMT2A
Diphenamide SCHEMBL39339 0.92 ALDH1A1 (0.55) KDM4EATMTDP1MEN1KMT2A
Diphenamide SCHEMBL9202269 0.92 ALDH1A1 (0.55) KDM4EATMTDP1MEN1KMT2A
Diphenamide SCHEMBL7756475 0.90 KDM4E (0.54) KDM4EATMTDP1MEN1KMT2A
Diphenamide SCHEMBL23924070 0.90 ALDH1A1 (0.53) KDM4EATMTDP1MEN1KMT2A
Diphenamide SCHEMBL11211674 0.90 ALDH1A1 (0.53) KDM4EATMTDP1MEN1KMT2A
Diphenamide SCHEMBL2051916 0.90 ALDH1A1 (0.53) KDM4EATMTDP1MEN1KMT2A
Diphenamide SCHEMBL23534079 0.90 ALDH1A1 (0.53) KDM4EATMTDP1MEN1KMT2A
Diphenamide SCHEMBL22345014 0.90 ALDH1A1 (0.53) KDM4EATMTDP1MEN1KMT2A
Diphenamide SCHEMBL10338756 0.90 ALDH1A1 (0.53) KDM4EATMTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346923-B1 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS DU PONT (US) 2012-11-21 EP disclosed
EP-2346923-A2 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E. I. du Pont de Nemours and Company (US) 2011-07-27 EP disclosed
EP-2346923-A2 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E. I. du Pont de Nemours and Company (US) 2011-07-27 EP disclosed
WO-2010048248-A3 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
WO-2010048248-A2 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-29 WO disclosed
WO-2010048248-A2 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-29 WO disclosed
US-20100099839-A1 FLUORINATED POLYOXYALKYLENE GLYCOL DIAMIDE SURFACTANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-04-22 US disclosed