Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CD40 | P25942 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769209 | 1.00 | GRIA1 (0.44) | GRIA1F2OPRD1OPRM1OPRK1 | |
| SCHEMBL29448567 | 0.86 | OPRD1 (0.55) | OPRD1OPRM1OPRK1 | |
| SCHEMBL16385079 | 0.86 | NPY4R (0.51) | OPRD1OPRM1OPRK1MMP8NPY1R | |
| SCHEMBL16384720 | 0.86 | NPY4R (0.51) | OPRD1OPRM1OPRK1MMP8NPY1R | |
| SCHEMBL29591811 | 0.82 | OPRD1 (0.52) | OPRD1OPRM1OPRK1CD40 | |
| SCHEMBL30468670 | 0.81 | CHRND (0.47) | GRIA1NAALAD2NPY1R | |
| SCHEMBL29707530 | 0.81 | CHRND (0.47) | GRIA1NAALAD2NPY1R | |
| SCHEMBL29590322 | 0.79 | OPRD1 (0.57) | OPRD1OPRM1OPRK1APC | |
| SCHEMBL1221588 | 0.79 | HDAC2 (0.57) | KDM4EHDAC2HDAC8 | |
| SCHEMBL15186015 | 0.78 | MMP2 (0.52) | GRIA1MMP2MMP8MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613755-A1 | LYSINE-SPECIFIC CHEMOENZYMATIC PROTEIN MODIFICATIONS USING MICROBIAL TRANSGLUTAMINASE | Novartis AG (CH) | 2020-02-26 | — | — | EP | disclosed |