Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 8/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 7/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5042475 | 0.81 | AR (0.43) | AOC3NOS2POLBHCAR3HRH3 | |
| SCHEMBL18708818 | 0.81 | GBA1 (0.47) | AOC3NOS3NOS2NOS1FEN1 | |
| SCHEMBL5133492 | 0.78 | AR (0.39) | FEN1ALOX5APPOLBHCAR3HRH3 | |
| SCHEMBL11625025 | 0.78 | NOS3 (0.41) | PIK3CDPIK3CANOS3NOS2NOS1 | |
| SCHEMBL5037391 | 0.77 | NOS3 (0.38) | NOS3NOS2NOS1FEN1ALOX5AP | |
| SCHEMBL179289 | 0.77 | AOC3 (0.35) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL9925938 | 0.77 | AOC3 (0.35) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL179514 | 0.76 | AOC3 (0.33) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL2789944 | 0.76 | ADK (0.40) | PIK3CDALOX5APPOLBHRH3 | |
| SCHEMBL12186836 | 0.75 | AOC3 (0.34) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613743-A1 | PROCESSES FOR THE PREPARATION OF 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES | Intellikine, LLC (US) | 2020-02-26 | — | — | EP | disclosed |