Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753513 | 0.92 | PDGFRB (0.59) | PDGFRBPDGFRAFGFR2EGFRKDR | |
| SCHEMBL30106512 | 0.92 | PDGFRB (0.59) | PDGFRBPDGFRAFGFR2EGFRKDR | |
| SCHEMBL21185680 | 0.81 | PDGFRB (0.60) | PDGFRBPDGFRAFGFR2EGFRKDR | |
| SCHEMBL21769423 | 0.77 | FGFR2 (0.57) | PDGFRBPDGFRAFGFR2KDR | |
| SCHEMBL30106509 | 0.77 | MET (0.58) | PDGFRBPDGFRAFGFR2EGFRKDR | |
| SCHEMBL371742 | 0.77 | MET (0.58) | PDGFRBPDGFRAFGFR2EGFRKDR | |
| SCHEMBL4462225 | 0.76 | PDGFRA (0.56) | PDGFRBPDGFRAFGFR2EGFRKDR | |
| SCHEMBL29073410 | 0.76 | KDR (0.56) | PDGFRBPDGFRAFGFR2KDR | |
| SCHEMBL14966472 | 0.76 | PDGFRB (0.58) | PDGFRBPDGFRAFGFR2EGFRKDR | |
| SCHEMBL23147176 | 0.75 | PDGFRB (0.54) | PDGFRBPDGFRAFGFR2EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842425-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020038460-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | 南京药捷安康生物科技有限公司 | 2020-02-27 | — | — | WO | disclosed |