⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702575 | 0.67 | — | — | |
| SCHEMBL19504412 | 0.67 | — | — | |
| SCHEMBL14098987 | 0.58 | LMNA (0.40) | — | |
| SCHEMBL275233 | 0.57 | — | — | |
| SCHEMBL364269 | 0.57 | — | — | |
| Ethane SCHEMBL28854344 | 0.56 | — | — | |
| SCHEMBL10184800 | 0.54 | — | — | |
| SCHEMBL2206447 | 0.54 | — | — | |
| SCHEMBL7339779 | 0.54 | — | — | |
| SCHEMBL9871570 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800767-B2 | Thyroid hormone receptor beta agonist compounds | Terns, Inc. (US) | 2020-10-13 | — | — | US | disclosed |
| US-20200062742-A1 | THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS | Terns, Inc. | 2020-02-27 | — | — | US | disclosed |