⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937046 | 0.89 | — | — | |
| SCHEMBL17796957 | 0.81 | — | — | |
| SCHEMBL17796938 | 0.81 | — | — | |
| SCHEMBL28245 | 0.81 | — | — | |
| SCHEMBL2735017 | 0.79 | GNAI3 (0.50) | — | |
| SCHEMBL19343096 | 0.76 | GNAI3 (0.48) | — | |
| SCHEMBL9965910 | 0.76 | GNAI3 (0.48) | — | |
| SCHEMBL6183469 | 0.74 | GNAI3 (0.40) | — | |
| SCHEMBL20047011 | 0.71 | ALDH1A1 (0.50) | — | |
| SCHEMBL19226519 | 0.71 | GNAI3 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399206-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | Redona Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | claimed |
| CN-118201914-A | 4-Oxo-1, 4-dihydroquinoline-3-carboxylic acid derivatives as PAPD5 and/or PAPD7 inhibitors | 雷多纳治疗公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116969923-A | Heteroaryl amino compounds, methods of preparation and use thereof | 北京鞍石生物科技有限责任公司 | 2023-10-31 | — | — | CN | claimed |
| WO-2023138412-A1 | FUSED PYRIMIDIN-2-AMINE COMPOUNDS AS CDK20 INHIBITORS | INSILICO MEDICINE IP LIMITED (CN) | 2023-07-27 | — | — | WO | claimed |
| US-11667635-B2 | Bicyclic heterocycles as FGFR4 inhibitors | INCYTE CORPORATION (US) | 2023-06-06 | — | — | US | claimed |
| WO-2023039089-A1 | PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES | TWENTYEIGHT-SEVEN, INC. (US) | 2023-03-16 | — | — | WO | claimed |
| CN-114787144-A | Pyridone compounds and methods for modulating protein kinases | 埃克塞里艾克西斯公司 | 2022-07-22 | — | — | CN | claimed |
| CN-114727983-A | Xanthine CB1 inhibitors | 金翅雀生物公司 | 2022-07-08 | — | — | CN | claimed |
| CN-110248939-B | Tyrosine amide derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2022-05-17 | — | — | CN | claimed |
| EP-3256464-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2022-05-11 | — | — | EP | claimed |
| EP-0149840-B1 | Substituted 5,11-dihydro-6H-dibenz[b,e]azepin-6-ones, method for their preparation and these compounds containing medicines | Dr. Karl Thomae GmbH (DE) | 1989-04-26 | — | — | EP | claimed |
| EP-0085899-B1 | PYRIDOBENZODIAZEPINONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1986-10-29 | — | — | EP | claimed |
| EP-0085892-B1 | SUBSTITUTED BENZODIAZEPINONES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-12-18 | — | — | EP | claimed |
| EP-0149840-A1 | Substituted 5,11-dihydro-6H-dibenz[b,e]azepin-6-ones, method for their preparation and these compounds containing medicines | Dr. Karl Thomae GmbH (DE) | 1985-07-31 | — | — | EP | claimed |
| US-4447434-A | ANTIULCER, ANTISECRETORY, OR ANTICHOLINERGIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1984-05-08 | — | — | US | claimed |
| US-4424226-A | ANTIULCER AGENTS | DR. KARL THOMAE GMBH (DE) | 1984-01-03 | — | — | US | claimed |
| US-4424225-A | ANTIULCER AGENTS | DR. KARL THOMAE GMBH (DE) | 1984-01-03 | — | — | US | claimed |
| EP-0086982-A1 | Substituted thienobenzodiazepinones, process for preparing them and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1983-08-31 | — | — | EP | claimed |
| EP-0085899-A2 | Pyridobenzodiazepinones, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1983-08-17 | — | — | EP | claimed |
| EP-0085892-A1 | Substituted benzodiazepinones, process for their preparation and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1983-08-17 | — | — | EP | claimed |