SCHEMBL21769711

SCHEMBL21769711

c1ccc(-c2ccccc2-c2c3ccccc3c(-c3cccc(-n4c(-c5ccccc5)nc5ccccc54)c3)c3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
GAA P10253 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
RECQL P46063 1/20 0.44
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 1/20 0.43
HPGD P15428 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.42
GRIA1 P42261 1/20 0.41
CACNG8 Q8WXS5 1/20 0.41
CACNG2 Q9Y698 1/20 0.41
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
MAPT P10636 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14000365 0.98 ESR1 (0.48) ESR1ESR2GAAMEN1KMT2A
SCHEMBL14363301 0.96 RECQL (0.48) ESR1ESR2GAAMEN1KMT2A
SCHEMBL26344226 0.94 MEN1 (0.46) ESR1ESR2GAAMEN1KMT2A
SCHEMBL26343561 0.93 ESR1 (0.50) ESR1ESR2GAAMEN1KMT2A
SCHEMBL26343523 0.92 ESR1 (0.49) ESR1ESR2GAAMEN1KMT2A
SCHEMBL9946420 0.91 ESR1 (0.56) ESR1ESR2GAAMEN1KMT2A
SCHEMBL13999915 0.91 RECQL (0.45) ESR1ESR2GAAMEN1KMT2A
SCHEMBL14000372 0.90 RECQL (0.47) ESR1ESR2GAAMEN1KMT2A
SCHEMBL14000007 0.90 RECQL (0.47) ESR1ESR2GAAMEN1KMT2A
SCHEMBL26344433 0.90 MAPT (0.54) ESR1ESR2GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-09-28 US disclosed
WO-2020040434-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309380-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, OR10J3, TMEM109 ESR1 124/4885ESR2 596/4885GAA 1650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.