SCHEMBL2176985

SCHEMBL2176985

ClCCc1ccccc1-c1nc2ccccc2[nH]1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.59
ALDH1A1 P00352 9/20 0.59
KDM4E B2RXH2 9/20 0.59
RAB9A P51151 8/20 0.59
GPR55 Q9Y2T6 1/20 0.59
SMN1; SMN2 Q16637 5/20 0.55
HPGD P15428 5/20 0.55
NPSR1 Q6W5P4 4/20 0.55
HSD17B10 Q99714 4/20 0.55
PKM P14618 2/20 0.55
GAA P10253 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
GLA P06280 1/20 0.55
MAPT P10636 1/20 0.55
HTT P42858 1/20 0.55
ABCB11 O95342 1/20 0.55
TP53 P04637 1/20 0.55
GBA1 P04062 1/20 0.50
CDK1 P06493 1/20 0.50
CDK2 P24941 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL541063 0.88 NPC1 (0.54) NPC1ALDH1A1KDM4ERAB9AGPR55
SCHEMBL12472220 0.87 NPC1 (0.63) NPC1ALDH1A1KDM4ERAB9AGPR55
SCHEMBL2178196 0.84 NPC1 (0.55) NPC1ALDH1A1KDM4ERAB9AGPR55
SCHEMBL2721000 0.81 ATR (0.62) NPC1ALDH1A1KDM4ERAB9AGPR55
SCHEMBL4166602 0.81 NPC1 (0.63) NPC1ALDH1A1KDM4ERAB9AGPR55
SCHEMBL28151705 0.81 NPC1 (0.63) NPC1ALDH1A1KDM4ERAB9AGPR55
SCHEMBL227743 0.79 NPC1 (0.78) NPC1ALDH1A1KDM4ERAB9AGPR55
SCHEMBL6756293 0.78 NPC1 (0.59) NPC1ALDH1A1KDM4ERAB9AGPR55
SCHEMBL20677803 0.78 GAA (0.57) NPC1ALDH1A1KDM4ERAB9AGPR55
SCHEMBL10512490 0.76 SMN1; SMN2 (0.52) NPC1ALDH1A1KDM4ERAB9AGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703243-B2 Anti-tarnish coatings ENTHONE INC. (US) 2014-04-22 US claimed
US-20120175022-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2012-07-12 US claimed
US-7972655-B2 Anti-tarnish coatings ENTHONE INC. (US) 2011-07-05 US claimed
US-20100291303-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2010-11-18 US claimed
EP-2220009-A1 ANTI-TARNISH COATING Enthone, Inc. (US) 2010-08-25 EP claimed
WO-2009067446-A1 ANTI-TARNISH COATING ENTHONE INC. (US) 2009-05-28 WO claimed
EP-1097618-B1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRYS METALS INC DBA ALPHA METALS INC (US) 2003-03-26 EP claimed
US-6294220-B1 IMPROVED CHEMICAL RESISTANCE CAN BE ACCOMPLISHED BY CONVERTING MOST OF THE CUPRIC-BASED ORGANOMETALLIC COMPOUND ON THE SURFACE INTO A CUPROUS-BASED ORGANOMETALLIC CONVERSION COATING. ALPHA METALS, INC. 2001-09-25 US claimed
EP-1097618-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. d/b/a ALPHA METALS, INC. (US) 2001-05-09 EP claimed
WO-2000002426-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. D/B/A ALPHA METALS, INC. (US) 2000-01-13 WO claimed
US-5362334-A Chemically forming protective layer on metal surface by treating with aqueous solution of benzimidazole 2-substituted with halogen, haloalkyl or haloaryl MACDERMID, INCORPORATED (US) 1994-11-08 US claimed
EP-2142485-B1 METALLIC SURFACE ENHANCEMENT MACDERMID ENTHONE INC (US) 2019-07-24 EP disclosed
US-8741390-B2 Metallic surface enhancement ENTHONE INC. (US) 2014-06-03 US disclosed
US-8703243-B2 Anti-tarnish coatings ENTHONE INC. (US) 2014-04-22 US disclosed
US-20120175022-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2012-07-12 US disclosed
US-20020106458-A1 Process for treating adhesion promoted metal surfaces with epoxy resins SHIPLEY COMPANY, L.L.C. 2002-08-08 US disclosed
EP-1209253-A2 Process for treating adhesion promoted metal surfaces with epoxy resins Shipley Co. L.L.C. (US) 2002-05-29 EP disclosed
US-6294220-B1 IMPROVED CHEMICAL RESISTANCE CAN BE ACCOMPLISHED BY CONVERTING MOST OF THE CUPRIC-BASED ORGANOMETALLIC COMPOUND ON THE SURFACE INTO A CUPROUS-BASED ORGANOMETALLIC CONVERSION COATING. ALPHA METALS, INC. 2001-09-25 US disclosed
EP-1097618-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. d/b/a ALPHA METALS, INC. (US) 2001-05-09 EP disclosed
WO-2000002426-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. D/B/A ALPHA METALS, INC. (US) 2000-01-13 WO disclosed