SCHEMBL2178196

SCHEMBL2178196

BrCCc1ccccc1-c1nc2ccccc2[nH]1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.55
RAB9A P51151 8/20 0.55
ALDH1A1 P00352 8/20 0.55
KDM4E B2RXH2 8/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
NPSR1 Q6W5P4 4/20 0.55
HPGD P15428 4/20 0.55
HSD17B10 Q99714 3/20 0.55
PKM P14618 2/20 0.55
GAA P10253 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
GPR55 Q9Y2T6 1/20 0.55
GLA P06280 1/20 0.55
MAPT P10636 1/20 0.55
HTT P42858 1/20 0.55
ABCB11 O95342 1/20 0.55
TP53 P04637 1/20 0.55
GBA1 P04062 1/20 0.50
CDK1 P06493 1/20 0.50
CDK2 P24941 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2176985 0.84 NPC1 (0.59) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL12472220 0.81 NPC1 (0.63) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL28151705 0.81 NPC1 (0.63) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL2721000 0.81 ATR (0.62) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL4166602 0.81 NPC1 (0.63) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL541063 0.80 NPC1 (0.54) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL227743 0.79 NPC1 (0.78) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL20677803 0.78 GAA (0.57) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL6756293 0.78 NPC1 (0.59) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL28294953 0.76 NPC1 (0.49) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8703243-B2 Anti-tarnish coatings ENTHONE INC. (US) 2014-04-22 US claimed
US-20120175022-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2012-07-12 US claimed
US-7972655-B2 Anti-tarnish coatings ENTHONE INC. (US) 2011-07-05 US claimed
US-20100291303-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2010-11-18 US claimed
EP-2220009-A1 ANTI-TARNISH COATING Enthone, Inc. (US) 2010-08-25 EP claimed
WO-2009067446-A1 ANTI-TARNISH COATING ENTHONE INC. (US) 2009-05-28 WO claimed
EP-1097618-B1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRYS METALS INC DBA ALPHA METALS INC (US) 2003-03-26 EP claimed
US-6294220-B1 IMPROVED CHEMICAL RESISTANCE CAN BE ACCOMPLISHED BY CONVERTING MOST OF THE CUPRIC-BASED ORGANOMETALLIC COMPOUND ON THE SURFACE INTO A CUPROUS-BASED ORGANOMETALLIC CONVERSION COATING. ALPHA METALS, INC. 2001-09-25 US claimed
EP-1097618-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. d/b/a ALPHA METALS, INC. (US) 2001-05-09 EP claimed
WO-2000002426-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. D/B/A ALPHA METALS, INC. (US) 2000-01-13 WO claimed
US-5362334-A Chemically forming protective layer on metal surface by treating with aqueous solution of benzimidazole 2-substituted with halogen, haloalkyl or haloaryl MACDERMID, INCORPORATED (US) 1994-11-08 US claimed
EP-2142485-B1 METALLIC SURFACE ENHANCEMENT MACDERMID ENTHONE INC (US) 2019-07-24 EP disclosed
US-8741390-B2 Metallic surface enhancement ENTHONE INC. (US) 2014-06-03 US disclosed
US-8703243-B2 Anti-tarnish coatings ENTHONE INC. (US) 2014-04-22 US disclosed
US-20120175022-A1 ANTI-TARNISH COATINGS ENTHONE INC. (US) 2012-07-12 US disclosed
US-20030209523-A1 Planarization by chemical polishing for ULSI applications APPLIED MATERIALS, INC. 2003-11-13 US disclosed
EP-1097618-B1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRYS METALS INC DBA ALPHA METALS INC (US) 2003-03-26 EP disclosed
US-6294220-B1 IMPROVED CHEMICAL RESISTANCE CAN BE ACCOMPLISHED BY CONVERTING MOST OF THE CUPRIC-BASED ORGANOMETALLIC COMPOUND ON THE SURFACE INTO A CUPROUS-BASED ORGANOMETALLIC CONVERSION COATING. ALPHA METALS, INC. 2001-09-25 US disclosed
EP-1097618-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. d/b/a ALPHA METALS, INC. (US) 2001-05-09 EP disclosed
WO-2000002426-A1 POST-TREATMENT FOR COPPER ON PRINTED CIRCUIT BOARDS FRY'S METALS, INC. D/B/A ALPHA METALS, INC. (US) 2000-01-13 WO disclosed