Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242794 | 0.92 | POLB (0.36) | HDAC1HDAC8HDAC6HDAC5ALDH1A1 | |
| SCHEMBL21769878 | 0.90 | MAPT (0.39) | HDAC1HDAC8HDAC6HDAC5ALDH1A1 | |
| SCHEMBL21769850 | 0.90 | HCRTR1 (0.35) | HCRTR1HCRTR2CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL2241378 | 0.87 | HDAC1 (0.36) | HDAC1HDAC8HDAC6HDAC5ALDH1A1 | |
| SCHEMBL3557373 | 0.87 | MAPT (0.36) | HDAC1HDAC8HDAC6HDAC5ALDH1A1 | |
| SCHEMBL2239362 | 0.86 | HDAC1 (0.38) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL21769886 | 0.86 | POLB (0.36) | HDAC1HDAC8HDAC6HDAC5HCRTR1 | |
| SCHEMBL21769877 | 0.86 | MAPT (0.41) | HDAC1HDAC8HDAC6HDAC5ALDH1A1 | |
| SCHEMBL21769567 | 0.86 | HDAC1 (0.38) | HDAC1HDAC8HDAC6HDAC5ALDH1A1 | |
| SCHEMBL21769738 | 0.86 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |