Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237823 | 0.94 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL21769881 | 0.93 | ALDH1A1 (0.39) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL21769743 | 0.92 | HDAC1 (0.38) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL2237688 | 0.91 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL21769740 | 0.90 | L3MBTL1 (0.33) | L3MBTL1MAPTMEN1LMNATP53 | |
| SCHEMBL21769572 | 0.90 | POLB (0.38) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL21769855 | 0.89 | MEN1 (0.39) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL3557373 | 0.88 | MAPT (0.36) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL2239362 | 0.88 | HDAC1 (0.38) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL21769877 | 0.88 | MAPT (0.41) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |