Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769887 | 0.93 | HDAC1 (0.36) | POLBTDP1HDAC1HDAC8HDAC6 | |
| SCHEMBL2239362 | 0.93 | HDAC1 (0.38) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| Amenamevir SCHEMBL2238614 | 0.93 | HDAC1 (0.37) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL21769877 | 0.91 | MAPT (0.41) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL2242794 | 0.91 | POLB (0.36) | POLBHDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL21769878 | 0.89 | MAPT (0.39) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL3557373 | 0.89 | MAPT (0.36) | TDP1HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL21769885 | 0.89 | POLB (0.37) | POLBTDP1ALDH1A1MAPTCETP | |
| SCHEMBL21769881 | 0.88 | ALDH1A1 (0.39) | HDAC1HDAC8HDAC6HDAC5L3MBTL1 | |
| SCHEMBL21769567 | 0.88 | HDAC1 (0.38) | POLBHDAC1HDAC8HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |