Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769884 | 0.88 | USP2 (0.36) | GAAKMT2ATP53SMN1; SMN2NPC1 | |
| SCHEMBL21769878 | 0.88 | MAPT (0.39) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL21769574 | 0.87 | HCRTR1 (0.31) | — | |
| SCHEMBL22055760 | 0.86 | NPC1 (0.36) | MAPTKMT2ASMN1; SMN2NPSR1KDM4E | |
| SCHEMBL21769853 | 0.82 | POLB (0.38) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL2242794 | 0.81 | POLB (0.36) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL21769850 | 0.79 | HCRTR1 (0.35) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL21769851 | 0.78 | HDAC1 (0.35) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL21769566 | 0.78 | KMT2A (0.37) | MAPTGAAALDH1A1HPGDKMT2A | |
| SCHEMBL21769567 | 0.78 | HDAC1 (0.38) | MAPTGAAALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |