Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 8/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769571 | 0.93 | SLC6A9 (0.36) | MAPT | |
| SCHEMBL3892309 | 0.93 | NPC1 (0.37) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL21769874 | 0.91 | MAPT (0.38) | ALDH1A1GAAKDM4ENPC1RAB9A | |
| SCHEMBL21769853 | 0.91 | POLB (0.38) | POLBCETPALDH1A1GAAKDM4E | |
| SCHEMBL21769886 | 0.89 | POLB (0.36) | POLBTDP1CETPALDH1A1GAA | |
| SCHEMBL17923455 | 0.89 | MAPT (0.37) | TDP1ALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL21769731 | 0.87 | KMT2A (0.40) | POLBALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL21769566 | 0.87 | KMT2A (0.37) | POLBALDH1A1GAAKDM4ENPC1 | |
| SCHEMBL21769573 | 0.86 | POLB (0.39) | POLBALDH1A1GAANPC1RAB9A | |
| SCHEMBL17923449 | 0.86 | SMN1; SMN2 (0.36) | POLBALDH1A1KDM4ENPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |