SCHEMBL21769976

SCHEMBL21769976

Cc1c(F)cc(I)cc1CN1CCOCC1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2A13 Q16696 7/20 0.50
HSD17B10 Q99714 2/20 0.42
CYP2C9 P11712 2/20 0.42
ALOX15 P16050 1/20 0.42
CNR2 P34972 3/20 0.42
CNR1 P21554 1/20 0.42
KMT2A Q03164 2/20 0.41
ATM Q13315 1/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29739597 0.82 CYP2A13 (0.50) CYP2A13HSD17B10CYP2C9ALOX15CNR2
SCHEMBL21756936 0.81 CYP2A13 (0.47) CYP2A13HSD17B10CYP2C9ALOX15CNR2
SCHEMBL26739641 0.79 CNR2 (0.48) CYP2A13HSD17B10CYP2C9ALOX15CNR2
SCHEMBL15546497 0.78 CYP2A13 (0.61) CYP2A13HSD17B10CYP2C9ALOX15KMT2A
SCHEMBL29739421 0.76 CTSB (0.57) CYP2A13CNR2CNR1KMT2AKDM4E
SCHEMBL29177411 0.76 CTSB (0.57) CYP2A13CNR2CNR1KMT2AKDM4E
SCHEMBL26360010 0.75 CYP2A13 (0.53) CYP2A13HSD17B10CYP2C9ALOX15CNR2
SCHEMBL29177403 0.73 CNR2 (0.43) CYP2A13HSD17B10CYP2C9ALOX15CNR2
SCHEMBL20465103 0.73 CYP2A13 (0.50) CYP2A13HSD17B10CYP2C9ALOX15CNR2
SCHEMBL10290331 0.72 CYP2A13 (0.61) CYP2A13HSD17B10CYP2C9ALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020039088-A2 NOVEL COMPOUNDS Xeniopro GmbH (DE) 2020-02-27 WO disclosed