SCHEMBL2177

SCHEMBL2177

C=CC(F)(F)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11079283 0.82
SCHEMBL1221868 0.72
SCHEMBL51392 0.72
SCHEMBL246972 0.72
SCHEMBL246973 0.72
SCHEMBL33041 0.70
SCHEMBL5523839 0.70
Benzene SCHEMBL8002830 0.70 ALDH1A1 (0.30)
SCHEMBL1221778 0.68 LMNA (0.32)
SCHEMBL7102163 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 707 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720212-A1 SAFEGUARD AGENT AND USE THEREOF Li, Haibo (CN) 2026-04-08 EP claimed
CN-119080768-A Method for promoting aza-indole difluoro allylation reaction by alkali 西安工程大学 2024-12-06 CN claimed
CN-119080668-A 3, 3-Bisindole dialkyl compound and synthetic method thereof 西安工程大学 2024-12-06 CN claimed
US-20240390719-A1 SAFEGUARD AGENT AND USE THEREOF LI HAIBO (CN) 2024-11-28 US claimed
WO-2024240215-A1 SAFEGUARD AGENT AND USE THEREOF LI HAIBO (CN) 2024-11-28 WO claimed
CN-118496169-A 11-Difluoromethyl dibenzo [ b, e ] [1,4] diazepine series compound promoted by visible light and preparation method and application thereof 江西师范大学 2024-08-16 CN claimed
CN-116730937-A 4-difluoroallyl isoxazole compound and preparation method thereof 华南理工大学 2023-09-12 CN claimed
CN-115611701-A Method for synthesizing difluorobromopropylene 中国矿业大学(北京) 2023-01-17 CN claimed
CN-111875732-A Low-temperature-resistant fluororubber and preparation method thereof 山东非金属材料研究所 2020-11-03 CN claimed
CN-108300419-A A kind of air-conditioning refrigerant and preparation method thereof 合肥嘉仕诚能源科技有限公司 2018-07-20 CN claimed
CN-105131183-B Preparation method of fluorosilicone optical diffusing agent 衢州市中通化工有限公司 2017-03-22 CN claimed
CN-104072691-B A kind of preparation method of the flame-retardant intumescent polystyrene with nucleocapsid structure 衢州市中通化工有限公司 2016-09-14 CN claimed
CN-104592942-A Flame-retardant type refrigerant and preparation method thereof JUHUA GROUP TECHNOLOGY CT 2015-05-06 CN claimed
US-8418530-B1 Compositions and methods for detecting leaks in HVAC/R systems MAINSTREAM ENGINEERING CORPORATION (US) 2013-04-16 US claimed
US-7960331-B2 Replacement solvents having improved properties and methods of using the same GRZYLL LAWRENCE R 2011-06-14 US claimed
US-7429557-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2008-09-30 US claimed
US-5759430-A HALOCARBONS SCIENCE & TECHNOLOGY CORPORATION @ UNM 1998-06-02 US claimed
US-5602262-A Process for the preparation of 2-deoxy-2,2-difluoro-β-D-ribo-pentopyranose ELI LILLY AND COMPANY (US) 1997-02-11 US claimed
EP-0727432-A1 Process for the preparation of 2-deoxy-2,2-difluoro-beta-d-ribo-pentopyranose ELI LILLY AND COMPANY (US) 1996-08-21 EP claimed
US-4299958-A HALOALKYLATION E. I. DUPONT DE NEMOURS AND COMPANY (US) 1981-11-10 US claimed