SCHEMBL21771971

SCHEMBL21771971

Cc1ccc(OC(=O)c2cccc(Cl)c2)c(N(Cc2ccccc2)Cc2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 3/20 0.43
MRGPRX4 Q96LA9 3/20 0.43
GAA P10253 2/20 0.43
KDM4E B2RXH2 2/20 0.43
KMT2A Q03164 1/20 0.43
TMEM97 Q5BJF2 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
TP53 P04637 2/20 0.42
LMNA P02545 3/20 0.41
ALOX5 P09917 1/20 0.41
MAPT P10636 3/20 0.40
THRB P10828 1/20 0.40
MAPK1 P28482 1/20 0.40
ATM Q13315 1/20 0.40
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21771979 0.90 MEN1 (0.47) NR3C1MRGPRX4KDM4EKMT2A
SCHEMBL21771938 0.74 TDP1 (0.50) NR3C1MRGPRX4KMT2ATMEM97SIGMAR1
SCHEMBL21771974 0.74 KMT2A (0.51) NR3C1GAAKMT2ALMNAMAPT
SCHEMBL21771967 0.72 KMT2A (0.47) NR3C1GAAKMT2ALMNAMAPT
SCHEMBL15705233 0.72 CYP2C19 (0.50) NR3C1GAAKDM4EKMT2ALMNA
SCHEMBL21771925 0.72 KMT2A (0.46) MRGPRX4GAAKDM4EKMT2ATP53
SCHEMBL14055345 0.71 KMT2A (0.59) GAAKDM4EKMT2ATP53LMNA
SCHEMBL20164254 0.70 LMNA (0.47) GAAKDM4EKMT2ATP53LMNA
SCHEMBL28471123 0.70 MAPT (0.44) NR3C1TP53LMNAMAPTMAPK1
SCHEMBL20164208 0.70 LMNA (0.47) GAAKDM4EKMT2ATP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed