SCHEMBL21771979

SCHEMBL21771979

Cc1ccc(OC(=O)c2ccccc2)c(N(Cc2ccccc2)Cc2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NR3C1 P04150 3/20 0.45
POLB P06746 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP2C19 P33261 1/20 0.42
TSPO P30536 1/20 0.42
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NPY1R P25929 1/20 0.41
NPY2R P49146 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21771971 0.90 NR3C1 (0.43) KMT2ANR3C1MRGPRX4KDM4E
SCHEMBL21771938 0.84 TDP1 (0.50) MEN1CYP3A4KMT2ATDP1L3MBTL1
SCHEMBL21771974 0.83 KMT2A (0.51) MEN1CYP3A4KMT2ATDP1L3MBTL1
SCHEMBL21771967 0.82 KMT2A (0.47) MEN1KMT2ATDP1NR3C1POLB
SCHEMBL15705233 0.79 CYP2C19 (0.50) MEN1KMT2ATDP1L3MBTL1NR3C1
SCHEMBL498193 0.77 KMT2A (0.53) MEN1CYP3A4KMT2ATDP1L3MBTL1
SCHEMBL28471123 0.76 MAPT (0.44) CYP3A4NR3C1POLBSMN1; SMN2CYP2C19
SCHEMBL9421256 0.75 KMT2A (0.52) MEN1KMT2AL3MBTL1MRGPRX4SMN1; SMN2
SCHEMBL18309427 0.75 CYP2C19 (0.46) MEN1KMT2AL3MBTL1NR3C1AKR1C3
SCHEMBL28663041 0.74 KMT2A (0.52) MEN1KMT2APOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed