⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140295 | 0.67 | — | — | |
| SCHEMBL14693689 | 0.67 | — | — | |
| SCHEMBL21244617 | 0.65 | EPHX1 (0.31) | — | |
| SCHEMBL7810433 | 0.64 | — | — | |
| SCHEMBL4654304 | 0.64 | — | — | |
| SCHEMBL8845272 | 0.61 | PREP (0.35) | — | |
| SCHEMBL4654318 | 0.60 | SHBG (0.35) | — | |
| SCHEMBL7300406 | 0.58 | ALDH1A1 (0.45) | — | |
| SCHEMBL16772831 | 0.58 | — | — | |
| SCHEMBL6518166 | 0.57 | EPHX1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149021-B2 | N-(azaaryl)cyclolactam-1-carboxamide derivative, preparation method therefor, and use thereof | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2021-10-19 | — | — | US | disclosed |
| US-20200071302-A1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2020-03-05 | — | — | US | disclosed |