Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2179821 | 0.95 | KCNA5 (0.39) | MAPTTP53KCNA5PSMB8PSMB5 | |
| Bicarbonate SCHEMBL2179815 | 0.95 | KCNA5 (0.39) | MAPTTP53KCNA5PSMB8PSMB5 | |
| Bicarbonate SCHEMBL2179811 | 0.94 | KCNA5 (0.41) | MAPTTP53KCNA5PSMB8PSMB5 | |
| SCHEMBL2177735 | 0.79 | KCNA5 (0.43) | MAPTTP53KCNA5PSMB8PSMB5 | |
| SCHEMBL2179299 | 0.76 | AOC3 (0.41) | MAPTALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2176940 | 0.74 | MAPT (0.43) | MAPTTP53KCNA5CHRM2CHRM1 | |
| SCHEMBL2634298 | 0.74 | AOC3 (0.46) | CHRM2CHRM1CHRM3L3MBTL1 | |
| SCHEMBL29950797 | 0.73 | MAPT (0.46) | MAPTTP53CHRM2CHRM1CHRM3 | |
| SCHEMBL2176604 | 0.72 | L3MBTL1 (0.44) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL2181081 | 0.72 | L3MBTL1 (0.41) | MAPTALDH1A1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080756-A1 | PROCESS FOR THE PREPARATION OF 1-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |