Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937534 | 0.88 | MAPT (0.45) | MAPTTP53MEN1KMT2ACHRM2 | |
| SCHEMBL17446980 | 0.83 | ALDH1A1 (0.51) | MAPTMEN1KMT2AKDM4EFFAR4 | |
| SCHEMBL2176940 | 0.83 | MAPT (0.43) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL21926455 | 0.82 | MAPT (0.48) | MAPTTP53CHRM2CHRM1CHRM3 | |
| SCHEMBL20911522 | 0.81 | MEN1 (0.43) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5776454 | 0.79 | MEN1 (0.51) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL20272734 | 0.78 | MAPT (0.42) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL1307531 | 0.78 | MAPT (0.46) | MAPTTP53CHRM2CHRM1CHRM3 | |
| SCHEMBL22730465 | 0.77 | MEN1 (0.48) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL17446871 | 0.77 | MEN1 (0.43) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |