SCHEMBL21772201

SCHEMBL21772201

C=CC(=O)NCCNC(=O)c1ccc(C(=O)c2ccc(O)c(O)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
SIRT1 Q96EB6 1/20 0.47
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
HDAC6 Q9UBN7 1/20 0.41
PTGS2 P35354 1/20 0.41
ERCC1 P07992 1/20 0.40
ERCC4 Q92889 1/20 0.40
APP P05067 1/20 0.40
TOP1 P11387 2/20 0.40
TERT O14746 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21772202 0.81 ALDH1A1 (0.46) LMNAALDH1A1HPGDPOLB
SCHEMBL16711125 0.80 ALDH1A1 (0.50) LMNAALDH1A1HPGDPOLB
SCHEMBL19888923 0.76 LMNA (0.59) LMNAALDH1A1HPGDHDAC6POLB
SCHEMBL28899489 0.75 CA12 (0.51) CA1CA2CA7CA9CA14
SCHEMBL21772208 0.75 HSD17B10 (0.47) ALDH1A1HPGDHDAC6
SCHEMBL13644432 0.74 TRPV1 (0.47) LMNAALDH1A1HPGDPOLB
SCHEMBL17927351 0.72 HDAC6 (0.56) LMNACA1CA2CA7CA9
SCHEMBL21772197 0.72 SCN1A (0.59) LMNAALDH1A1HPGDPTGS2POLB
SCHEMBL24440484 0.72 HDAC6 (0.60) ALDH1A1CA1CA2CA7CA9
SCHEMBL29633482 0.72 HDAC6 (0.60) ALDH1A1CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10703835-B2 Hyperbranched cationic mussel-imitated polymer and method of preparing the same Sichuan Huili Industry Co., Ltd. (CN) 2020-07-07 US claimed
US-20200071433-A1 HYPERBRANCHED CATIONIC MUSSEL-IMITATED POLYMER AND METHOD OF PREPARING THE SAME Sichuan Huili Industry Co., Ltd. (CN) 2020-03-05 US claimed
US-11318724-B2 Film for medicine packaging and method of preparing the same Sichuan Huili Industry Co., Ltd. (CN) 2022-05-03 US disclosed
US-20200282714-A1 FILM FOR MEDICINE PACKAGING AND METHOD OF PREPARING THE SAME SICHUAN HUILI IND CO LTD (CN) 2020-09-10 US disclosed
US-10703080-B2 Film for medicine packaging and method of preparing the same Sichuan Huili Industry Co., Ltd. (CN) 2020-07-07 US disclosed
US-10703835-B2 Hyperbranched cationic mussel-imitated polymer and method of preparing the same Sichuan Huili Industry Co., Ltd. (CN) 2020-07-07 US disclosed
US-20200070485-A1 FILM FOR MEDICINE PACKAGING AND METHOD OF PREPARING THE SAME Sichuan Huili Industry Co., Ltd. (CN) 2020-03-05 US disclosed
US-20200071433-A1 HYPERBRANCHED CATIONIC MUSSEL-IMITATED POLYMER AND METHOD OF PREPARING THE SAME Sichuan Huili Industry Co., Ltd. (CN) 2020-03-05 US disclosed