SCHEMBL21772309

SCHEMBL21772309

CC=C=C(C)C(=O)OCCCO

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
ALDH1A1 P00352 1/20 0.32
ACHE P22303 6/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28004092 0.95 TSHR (0.37) TSHRALDH1A1ACHE
SCHEMBL1950777 0.89 TSHR (0.38) TSHRACHE
SCHEMBL678652 0.85 ALDH1A1 (0.50) TSHRALDH1A1ACHEATM
SCHEMBL10620681 0.82 TSHR (0.56) TSHRALDH1A1ACHEATM
SCHEMBL9858359 0.81 HCAR2 (0.38) TSHRALDH1A1ATM
SCHEMBL29168471 0.79 THRB (0.32)
SCHEMBL27841851 0.76 CHRM1 (0.46) ALDH1A1
SCHEMBL601419 0.76 TSHR (0.38) TSHRALDH1A1ACHEATM
SCHEMBL11434518 0.76 TSHR (0.38) TSHRALDH1A1ACHEATM
SCHEMBL11681441 0.73 TSHR (0.36) TSHRALDH1A1ACHEATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235275-A2 POLYMERIC COMPOSITION EXHIBITING NANOGRADIENT OF REFRACTIVE INDEX Staar Surgical Company (US) 2023-08-30 EP disclosed
EP-3837571-B1 POLYMERIC COMPOSITION EXHIBITING NANOGRADIENT OF REFRACTIVE INDEX STAAR SURGICAL CO (US) 2023-08-02 EP disclosed
US-20220363795-A1 POLYMERIC COMPOSITION EXHIBITING NANOGRADIENT OF REFRACTIVE INDEX STAAR SURGICAL COMPANY 2022-11-17 US disclosed
EP-3837571-A1 POLYMERIC COMPOSITION EXHIBITING NANOGRADIENT OF REFRACTIVE INDEX Staar Surgical Company (US) 2021-06-23 EP disclosed
US-20200377635-A1 POLYMERIC COMPOSITION EXHIBITING NANOGRADIENT OF REFRACTIVE INDEX STAAR SURGICAL COMPANY 2020-12-03 US disclosed
US-10774164-B2 Polymeric composition exhibiting nanogradient of refractive index STAAR SURGICAL COMPANY (US) 2020-09-15 US disclosed
US-20200071440-A1 POLYMERIC COMPOSITION EXHIBITING NANOGRADIENT OF REFRACTIVE INDEX STAAR SURGICAL COMPANY 2020-03-05 US disclosed