Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180162 | 0.98 | EGLN1 (0.58) | EGLN1CA12CA1CA2CA9 | |
| SCHEMBL2176387 | 0.94 | EGLN1 (0.62) | EGLN1ALDH1A1SMN1; SMN2CYP2D6GAA | |
| SCHEMBL13552393 | 0.92 | EGLN1 (0.63) | EGLN1MEN1KMT2ACA12CA1 | |
| SCHEMBL2032859 | 0.90 | EGLN1 (0.61) | EGLN1MEN1KMT2ACA12CA1 | |
| SCHEMBL11596790 | 0.90 | EGLN1 (0.61) | EGLN1MEN1KMT2ACA12CA1 | |
| SCHEMBL9408944 | 0.86 | EGLN1 (0.57) | EGLN1PLA2G2AEPHX1ACHEFAAH | |
| SCHEMBL12495312 | 0.85 | EGLN1 (0.65) | EGLN1ALDH1A1SMN1; SMN2CYP2D6GAA | |
| SCHEMBL11408936 | 0.84 | EPHX1 (0.57) | EGLN1PLA2G2AEPHX1ACHEFAAH | |
| SCHEMBL15682714 | 0.84 | EPHX1 (0.57) | EGLN1PLA2G2AEPHX1ACHEFAAH | |
| SCHEMBL2487820 | 0.84 | EPHX1 (0.57) | EGLN1PLA2G2AEPHX1ACHEFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765881-B2 | Methods of making polydiorganosiloxane polyoxamide copolymers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-01 | — | — | US | disclosed |
| EP-2519563-B1 | METHODS OF MAKING POLYDIORGANOSILOXANE POLYOXAMIDE COPOLYMERS | 3M INNOVATIVE PROPERTIES CO (US) | 2013-11-06 | — | — | EP | disclosed |
| EP-2519563-A1 | METHODS OF MAKING POLYDIORGANOSILOXANE POLYOXAMIDE COPOLYMERS | 3M Innovative Properties Company (US) | 2012-11-07 | — | — | EP | disclosed |
| US-20120271025-A1 | METHODS OF MAKING POLYDIORGANOSILOXANE POLYOXAMIDE COPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-10-25 | — | — | US | disclosed |
| WO-2011082069-A1 | METHODS OF MAKING POLYDIORGANOSILOXANE POLYOXAMIDE COPOLYMERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120271025-A1 | METHODS OF MAKING POLYDIORGANOSILOXANE POLYOXAMIDE COPOLYMERS | PPOX, PARG, PAM | EGLN1 322/4885MEN1 3144/4885KMT2A 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.