SCHEMBL2177466

SCHEMBL2177466

CC(C)(C)c1cc(-c2nc3cc(Cl)ccc3s2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.51
GAA P10253 1/20 0.51
SI P14410 1/20 0.51
MGAM2 Q2M2H8 1/20 0.51
AGPAT2 O15120 4/20 0.44
HSP90AA1 P07900 1/20 0.44
PPARA Q07869 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
SENP7 Q9BQF6 2/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.38
IDO1 P14902 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29946134 1.00 MGAM (0.51) MGAMGAASIMGAM2AGPAT2
SCHEMBL2354486 0.88 MGAM (0.51) MGAMGAASIMGAM2AGPAT2
SCHEMBL2774898 0.84 TNF (0.55) GAAHSP90AA1SMN1; SMN2NPSR1
SCHEMBL7642933 0.77 AGPAT2 (0.47) MGAMGAASIMGAM2AGPAT2
SCHEMBL29269889 0.73 SENP7 (0.41) MGAMGAASIMGAM2AGPAT2
SCHEMBL12471100 0.72 MGAM (0.70) MGAMGAASIMGAM2AGPAT2
SCHEMBL4366547 0.71 HSP90AA1 (0.49) MGAMGAASIMGAM2HSP90AA1
SCHEMBL12470723 0.71 GAA (0.68) MGAMGAASIMGAM2AGPAT2
SCHEMBL13379223 0.70 HSP90AA1 (0.43) MGAMGAASIMGAM2HSP90AA1
SCHEMBL1938923 0.70 MGAM (0.50) MGAMGAASIMGAM2AGPAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240384024-A1 CONDUIT TUBE AND THERMOPLASTIC POLYESTER ELASTOMER RESIN COMPOSITION TOYOBO MC CORPORATION (JP) 2024-11-21 US disclosed
EP-4400545-A1 CONDUIT TUBE AND THERMOPLASTIC POLYESTER ELASTOMER RESIN COMPOSITION TOYOBO MC Corporation (JP) 2024-07-17 EP disclosed
WO-2024101133-A1 FLAME RETARDANT POLYESTER ELASTOMER RESIN COMPOSITION 東洋紡エムシー株式会社 2024-05-16 WO disclosed
CN-115135720-B Polyester elastomer resin composition 东洋纺MC株式会社 2024-04-23 CN disclosed
WO-2013101624-A1 PRINTABLE MOLDED ARTICLES MADE FROM A POLYOXYMETHYLENE POLYMER COMPOSITION TICONA LLC (US) 2013-07-04 WO disclosed
US-8227053-B2 Optically compensatory film, polarizing plate and liquid-crystal display FUJIFILM CORPORATION (JP) 2012-07-24 US disclosed
US-8030417-B2 Process for producing polyester-polycarbonate type thermoplastic polyester elastomer and polyester-polycarbonate type thermoplastic polyester elastomer TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-10-04 US disclosed
US-7973124-B2 Method for producing thermoplastic polyester elastomer, thermoplastic polyester elastomer composition, and thermoplastic polyester elastomer TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-07-05 US disclosed
US-20100041858-A1 PROCESS FOR PRODUCING POLYESTER-POLYCARBONATE TYPE THERMOPLASTIC POLYESTER ELASTOMER AND POLYESTER-POLYCARBONATE TYPE THERMOPLASTIC POLYESTER ELASTOMER TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-02-18 US disclosed
US-7651743-B2 Cellulose acylate film, manufacturing method of cellulose acylate film, optically compensatory sheet, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-26 US disclosed
US-20090203871-A1 METHOD FOR PRODUCING THERMOPLASTIC POLYESTER ELASTOMER, THERMOPLASTIC POLYESTER ELASTOMER COMPOSITION, AND THERMOPLASTIC POLYESTER ELASTOMER TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-08-13 US disclosed
US-20080158489-A1 Optically-Compensatory Film, Polarizing Plate And Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20070054977-A1 Coating composition and method of forming coating film KANSAI PAINT CO., LTD. (JP) 2007-03-08 US disclosed
US-20060286313-A1 Cellulose acylate film, manufacturing method of cellulose acylate film, optically compensatory sheet, polarizing plate and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2006-12-21 US disclosed
US-6770125-B2 Reversible thermochromic composition NEW PRISMATIC ENTERPRISE CO., LTD. (TW) 2004-08-03 US disclosed
US-6692821-B2 Acrylic resin laminated film and laminated molding using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-02-17 US disclosed
US-20020136853-A1 Acrylic resin laminated film and laminated molding using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-26 US disclosed